Zholion provides leak detection equipment for sale for pharmaceutical packaging, medical devices and container closure integrity testing (CCIT). Our leak detector range includes vacuum decay, high voltage leak detection, helium leak detection, pressure decay and positive/negative pressure testing systems.

Whether you need a laboratory pharmaceutical leak detector for method development or automated leak testing equipment for routine quality control, we can recommend a system based on your package type, product state, target leak size and testing throughput.

Our Leak Tester equipment can be configured for vials, ampoules, prefilled syringes, cartridges, bottles, BFS containers, flexible packages and other pharmaceutical container closure systems.

Pharmaceutical Leak Detection Equipment

Selecting the correct leak detection equipment depends on the package material, product state, expected defect size and whether non-destructive testing is required.

Zholion offers multiple leak detection technologies for pharmaceutical package development, CCIT method validation and routine quality control.

Leak Detection Technologies Available

Vacuum Decay Leak Detection Equipment

Vacuum decay is a deterministic and non-destructive test method that detects leaks by monitoring pressure changes inside a sealed test chamber.

The MC-V12 Vacuum Decay Leak Detector is recommended for laboratories requiring quantitative package integrity testing, while the RC-V12 Automatic Vacuum Decay Leak Detector is designed for applications requiring higher throughput and standardized sample handling.

Vacuum decay is widely used for pharmaceutical CCIT and is particularly suitable for many rigid and semi-rigid package configurations.

High Voltage Leak Detector

The MC-E23 High Voltage Leak Detector is designed for suitable liquid-filled pharmaceutical packages.

High Voltage Leak Detection (HVLD) evaluates changes in electrical response across a non-conductive package containing a sufficiently conductive liquid product.

Typical applications include:

● Ampoules
● Liquid-filled vials
● Prefilled syringes
● Cartridges
● Selected BFS containers

HVLD provides rapid, non-destructive testing and can be considered when both the product and package meet the electrical requirements of the method.

Helium Leak Detection Equipment

The MC-H52 Helium Leak Detector uses helium tracer gas for quantitative measurement of very small leaks.

Helium leak testing is particularly useful for:

● Package development
● Closure system comparison
● Method development
● Microleak investigations
● High-sensitivity leak-rate measurement

Compared with routine production-oriented methods, helium testing is often selected when very high sensitivity and quantitative leak-rate data are required.

Pressure and Vacuum Leak Test Equipment

For applications requiring positive pressure, negative pressure or combined testing modes, Zholion provides the MC-B82 Series, MC-D73 and MC-DUO(VP).

These systems can support package sealing evaluation, pressure resistance studies, gross leak detection and package development depending on the selected configuration and fixture.

Applications of Our Leak Detector Machines

Zholion pharmaceutical leak detection equipment can be configured for different package formats, including:

● Pharmaceutical vials
● Glass ampoules
● Prefilled syringes
● Cartridges
● BFS containers
● IV bags and flexible packages
● Bottles and containers
● Medical device packages
● Injection device components

Package geometry, materials, closure design, fill state and internal volume can all affect leak test performance. For this reason, we recommend providing package drawings or samples before selecting the final equipment configuration.

How to Choose Leak Detection Equipment

Before purchasing a leak detector machine, consider the following factors:

1. Package Type

Determine whether the package is rigid, semi-rigid or flexible and identify potential leak locations around the body, seal or closure.

2. Product State

Liquid-filled, lyophilized, dry powder and empty packages may require different leak detection technologies.

3. Required Leak Detection Level

The required detection capability should be established according to the package integrity risk and intended application.

4. Destructive vs. Non-Destructive Testing

If samples need to be retained for stability studies or further analysis, a non-destructive leak testing technology may be preferred.

5. Testing Throughput

Laboratory method development may only require offline equipment, while routine production quality control may require faster or automated testing.

6. Validation Requirements

For pharmaceutical CCIT, the selected equipment and method should support development of repeatable test parameters, positive control studies and defined acceptance criteria.

Deterministic methods such as vacuum decay and HVLD are widely used because they provide objective, instrument-based measurements rather than relying primarily on visual operator interpretation. (pti-ccit.com)

Why Zholion as Your Leak Detection Equipment Supplier?

Founded in 2005, Zholion specializes in pharmaceutical and medical device container closure integrity testing and gas analysis.

We provide more than individual leak detection equipment. Our technical support covers the complete process from package evaluation to implementation.

● Leak detection method selection
● Equipment configuration
● Package-specific fixture development
● Positive control selection
● Method development support
● Installation and operator training
● Testing and troubleshooting support
● Laboratory and automated equipment options

This enables pharmaceutical manufacturers, laboratories and packaging development teams to select equipment based on the actual product-package system rather than using one leak test method for every application.

FAQ – Leak Detection Equipment for Sale

What leak detection equipment is used for pharmaceutical packaging?

Common pharmaceutical leak detection equipment includes vacuum decay leak detectors, high voltage leak detectors, helium leak detectors and pressure decay systems. The correct equipment depends on the package material, product state and required detection capability.

Which leak detector is suitable for pharmaceutical vials?

Vacuum decay can be suitable for many sealed vials. HVLD may be appropriate for liquid-filled vials with suitable electrical properties, while helium leak detection can be selected when very high sensitivity or quantitative leak-rate measurement is required.

Do you offer non-destructive leak detection equipment?

Yes. Zholion provides non-destructive testing options including vacuum decay and HVLD for suitable product-package systems.

Can one leak detector test different container sizes?

In many cases, yes. Different test chambers, fixtures or sample holders can be configured according to package size and geometry.

Can Zholion customize leak testing fixtures?

Yes. Test chambers, holders, fixtures and connectors can be designed according to package dimensions, closure configuration and selected leak detection method.

What information should I provide before requesting a quotation?

Please provide the package type, dimensions, material, product state, expected leak level, testing method if known and required testing throughput. Package drawings or physical samples can also help with equipment and fixture selection.

Looking for Leak Detection Equipment for Sale?

Tell us what package you need to test.

Send Zholion your package type, dimensions, product state, target leak level and required testing throughput. Our technical team can recommend suitable pharmaceutical leak detection equipment, test methods and package-specific fixtures.

Contact Zholion for Leak Detection Equipment Pricing & Selection.